Viruses – seeking and destroying the tumor program

Destroying Civilization, Destroying Nature

Tumor Viruses and Differentiation

The UCLA Symposia on Molecular and Cellular Biology have consistently put forward volumes of the highest caliber. This, the fifth of seven such symposia published to date, certainly upholds that quality. There are, however, two structural shortcomings in this book. The first is that over half of the volume has previously been published in the Journal of Cell Biology during 1982 and 1983 (volume...

Tumor viruses.

It has been known for many years that infection of an experimental animal with one of a relatively small group of viruses somehow resulted in the appearance of gross tumors. Because of this and the known intimate relationships between the infecting virus and the functions of the cell it invades, many scientists have hypothesized that cancer in man may well be of viral etiology. Yet even today w...

Inactivation of Human Erythrocyte Agglutinogens M and N by Influenza Viruses and Receptor-destroying Enzyme.

The ability of influenza viruses and receptor-destroying enzyme from Vibrio cholerae (R.D.E.) to remove the serologically specific heterogenetic mononucleosis receptor from sheep erythrocytes has recently been reported.1 It was of interest, therefore, to investigate the effect of influenza viruses and R.D.E. upon serologically recognized receptors of human erythrocytes. The present paper report...

The RNA tumor viruses--background and foreground.

The members of the RNA tumor virus (or leukovirus) group of animal viruses replicate via a DNA intermediate and transmit their information stably in cells as DNA. Although some of these viruses are capable of inducing neoplastic transformation, others are not. These viruses may be related to spontaneous neoplasia, but the relationship is that of analogy rather than etiology. The relationship of...